Bioconversion and Deodorization of Shrimp Processing Waste by Xerocomus badius and Inhibitory Activity of Converted Product on Angiotensin I-converting Enzyme

Angiotensin-i Converting Enzyme (ace) Inhibitory Activity and Antioxidant Activity of Fermented Fish Product Ngari as Influenced by Fermentation Period

Ngari is a traditional salt-free fermented fish product in the north eastern region of India. During the fermentation, breakdown of protein leads to release of the peptides with specific sequences which may have potential anti-hypertensive and antioxidant properties. In the present investigation, influence of fermentation period on antihypertensive properties (angiotensin-I converting enzyme (A...

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

Angiotensin-I converting enzyme (ACE), a two-domain dipeptidylcarboxypeptidase, is a key regulator of blood pressure as a result of its critical role in the renin-angiotensin-aldosterone and kallikrein-kinin systems. Hence it is an important drug target in the treatment of cardiovascular diseases. ACE is primarily known for its ability to cleave angiotensin I (Ang I) to the vasoactive octapepti...

Antioxidant and angiotensin I-converting enzyme inhibitory activities of northern shrimp (Pandalus borealis) by-products hydrolysate by enzymatic hydrolysis

In the present study, we investigated to the antioxidant and angiotensin I-converting enzyme (ACE) inhibitory activities of the northern shrimp (Pandalus borealis) by-products (PBB) hydrolysates prepared by enzymatic hydrolysis. The antioxidant and ACE inhibitory activities of five enzymatic hydrolysates (alcalase, protamex, flavourzyme, papain, and trypsin) of PBB were evaluated by the 2, 2′-a...

Analysis method of the angiotensin-I converting enzyme inhibitory activity based on micellar electrokinetic chromatography.

A micellar electrokinetic chromatography (MEKC) method was developed for estimating the angiotensin-I converting enzyme (ACE) inhibitory activity by separating the hippuric acid liberated in the ACE reaction mixture in the presence of an inhibitor, captopril. The hippuric acid was successfully separated and detected by MEKC with a 25 mM sodium dodecyl sulfate solution in a 25 mM phosphate-50 mM...

Angiotensin Converting Enzyme in Sarcoidosis